Nguyen Thi Thuy Hanh, MD, MPH – Study Coordinator
Dr. Nguyen has 17 years of experience working in tuberculosis (TB) clinical trials and TB diagnosis research. Since 2010, she has been a study coordinator at the Research Collaboration Unit between the University of California San Francisco (UCSF) and Vietnam National Tuberculosis Control Program (VNTP)/Center for Promotion of Advancement of Society (CPAS). She has contributed to several research projects funded by organizations such as the National Institutes of Health (NIH), the CDC, MSF and PIH. Her research projects include evaluating newly approved drugs for multidrug-resistant TB, testing CRP-based TB triage testing, and assessing the efficacy and safety of high-dose Rifapentine and Moxifloxacin for the treatment of TB. Dr. Nguyen has also played a pivotal role in conducting a randomized, open-label, controlled phase 3 clinical trial studying Rifapentine-containing treatment shortening regimens for pulmonary tuberculosis at Vietnam site. Additionally, she conducted a study to evaluate the accuracy of the Quantiferon test in active TB cases and evaluated the performance of Hain GenoType MTBDRplus assay for the detection of MTB and drug resistance.
Before joining CPAS, Dr. Nguyen worked as a project officer at the International Medical Centre of Japan at Bach Mai Hospital from 2006 to 2010. She contributed to projects on medical and research collaboration between Japan and Vietnam, such as prevalence and risk factors for tuberculosis infection among hospital workers in Vietnam, or the use of Interferon-gamma assay using tuberculosis-specific antigens for diagnostic decision making in smear-negative pulmonary tuberculosis. From 2004 to 2006, Dr. Nguyen worked as a project officer at the Vietnam National Institute of Occupational and Environmental Health, where she gained valuable experience in occupational health and safety.
Dr. Nguyen is a dedicated and motivated professional who is passionate about improving the diagnosis, treatment, and prevention of TB
Education
MD – Hanoi Medical University
MPH – Hanoi Medical University
Selected Research Projects
Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB with Fluoroquinolone Resistance (Q) (endTB-Q). Funded by UNITAID through MSF and PIH. (2020 – 12/2023). Role: Site Coordinator
Prospective, Duration-Randomized, Partially Blinded, Phase 2 Study of the Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine for Treatment of Patients with MDR-TB (DRAMATIC). Funded by NIH (8/2020 – 5/2025). Role: Coordinator
Rapid Research in Diagnostics Development for Tuberculosis Network (R2D2 TB Network). Funded by NIH (8/2020 – 5/2025). Role: Monitor
CRP-based TB Triage Testing. Funded by NIH/NIAID (7/2021-7/2023). Role: Coordinator
CRP-based TB Triage Testing. Funded by UCSF Nina Ireland Program in Lung Health (2019-2020). Role: Coordinator
TBTC Study 31. A5349: Rifapentine-containing treatment shortening regimens for pulmonary tuberculosis: A randomized, open-label, controlled phase 3 clinical trial. Funded by CDC (2015-2019). Role: Coordinator
Sub-Study: Population Pharmacokinetic and Pharmacodynamic Study of Efficacy and Safety of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis in the Study 31 Treatment Trial: Intensive PK Sampling. Funded by CDC (2016-2020). Role: Coordinator
Sub-Study: M. tuberculosis RNA transcriptomic expression profiling in sputum of patients with active pulmonary TB enrolled in Study 31 / A5349 (STEPS-EXPRESS 31). Funded by CDC (2016-2019). Role: Coordinator
An Observational Study of Individuals Treated for Pulmonary Tuberculosis (TB). Funded by CDC (2015-2020). Role: Coordinator
Evaluation of Rifapentine – containing regimen for intensive phase treatment of pulmonary tuberculosis (Study 29x: taking drugs with food). Funded by CDC (2012-2013). Role: Coordinator
Evaluation of Hain GenoType® MTBDRplus assay performance for detection of MTB and drug resistance as part of screening and enrollment procedures for TBTC Study 29x in Hanoi, Vietnam (2012-2013). Role: Coordinator
Evaluating the Accuracy of the Quantiferon Test Boosted with Immunomodulators in Active Tuberculosis. Funded by UCSF/Stanford (2012 – 2013). Role: Coordinator
TB Trial Consortium Study 29: Evaluation of Rifapentine – containing regimen for intensive phase treatment of pulmonary tuberculosis (Study 29: taking drugs without food). Funded by CDC (2010-2011). Role: Coordinator
Interferon-gamma assay using tuberculosis-specific antigens to diagnostic decision making in smear-negative pulmonary tuberculosis. Role: Project officer
Prevalence and risk factors for tuberculosis infection among hospital workers in Vietnam. Role: Project officer
Interferon gamma response to Mycobacterium tuberculosis-specific antigens in the clinical course of smear-positive tuberculosis. Role: Project officer